Implantable and Degradable Wireless Passive Protein-Based Tactile Sensor for Intracranial Dynamic Pressure Detection

Implantable sensors normally require devices with excellent biocompatibility and flexibility as well wireless communication. Silk fibroin (SF) is an ideal material for implantable electronic due to its natural biodegradability biocompatibility. In this work, we prepared SF protein materials different force/chemical properties through mesoscopic regulation, realized full replacement from substrate dielectric elastomer sensors, so achieve controlled complete degradation. tests simulating intracranial pressure, the SF-based all-protein sensor achieved a sensitivity up 4.44 MHz/mmHg in pressure range of 0–20 mmHg. addition, insensitive temperature changes tissue environments, can work stably simulated body fluids long time. This provides passive, solution sensors.